1. Refer to peer reviewed literature to describe the mode of action of one cell signalling pathway (one page), each student will write about an assigned pathway.
2. Construct a table showing the history of discovery of this pathway, with an emphasis on the most recent discoveries (one page), be sure to give attribution to the researchers who originally published the discoveries.
Therefore be very careful in selecting relevant material to include in your assignment. Title page, references, figure and table legends (and/or additional figures or tables) do not contribute to the total page count (although they must be included within the document). Source your literature primarily from peer review journal articles, use database services such as PubMed, Web of Science or Google Scholar to find relevant articles. Use Harvard style referencing. Figures and tables should be drawn/tabulated by yourself to highlight or summarise key aspects of you discussion. Your research into the topic is self directed, think of some questions to ask yourself whilst you read the literature such as: What is the purpose of the signalling pathway? How does it operate? To what extent is the pathway conserved across species? What is known about the pathway in model organisms? Were model organisms important in gaining an understanding of the pathway? What biological techniques were important in delineating the pathway? What was the timeline of discovery? How well is the pathway understood? What are the current areas of research being pursued in regard to this pathway? Is the pathway implicated in disease? Is there a family of proteins involved in the pathway? Does the pathway exhibit different characteristics in different tissue? How well is the pathway defined? What research tools are available to study this pathway? What aspects of this pathway are shared with other signalling pathways.
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